Peritoneal Tumour Service Patient Day Christie 21st September
Peritoneal Tumour Service Patient Day Christie 21st September 2016 Research Professor Andrew G Renehan PhD FRCS FRCS(GenSurg) Colorectal & Peritoneal Oncology Centre, The Christie NHS Foundation Trust; Division of Molecular & Clinical Cancer Sciences, School of Medical Sciences, University of Manchester; Manchester Academic Health Science Centre Research framework 1. Pseudomyxoma peritonei (PMP) Appendiceal tumours 2. Appendiceal cancers 3. Peritoneal metastases from colorectal cancer Complications & mortality: cyto +HIPEC for PMP
No. of pts Complications (%) Mortality (%) Washington 501 40 2 Amsterdam 103 54
3 (4) 1 (0.4) 1 (1) 10.4% 17.6% UK & Ire. Peritoneal Tumour Services Reference treatment centres (appendiceal & PMCR) Hampshire Hospitals NHS FT The Christie NHS FT Other treatment centres (PMCR only) Mater Misericordiae University Hospital, Dublin Ninewells Hospital and Medical School, Dundee
Good Hope Hospital, Birmingham 6 Study Aim To develop a robust and reproducible framework in which to undertake a phase III trial in patients with PMCR suitable for CRS with or without HIPEC IDEAL Framework As CRS with HIPEC is a complex multicomponent component intervention, we propose to address this agenda using the principles of the IDEAL framework Idea Development Exploration Assessment
Long-term Study PMP: laboratory research Andrew Renehan Darren Roberts Peter Stern PMP: laboratory research Bowel cancer >50% Tumour PMP < 5% Tumour PMP cells Mucin
0.14 0.22 0.37 0.61 1.0 Future studies 1. Cell line high-through drug screens in PMP 2. Determine key driver genes in PMP 3. Characterise colorectal peritoneal metastases cancer with
Summary 1. Prospective outcome analyses 2. Trials (multi-step process) 3. Laboratory research Acknowledgements The Christie Colorectal & Peritoneal Oncology team Halstead ODwyer Butler Wilson Brown Selvasekar Fulford Tyrell Aziz Secretaries Minicozzi MDT coordinators Deshpande Kochhar
Mullin Saunders Braun Mullamitha Anaesthetists Theatre staff Perfusionists CCU staff Ward staff Chakrabarty Bowel Disease Research Foundation Christie data team Morrison Punnett Crichton Fernandez de-Silva
University of Manchester Emsley (statistics & methodology) Science laboratory Stern Roberts Brognard The patients
- Identify basic trig identities. Use basic trig identities to . find trig values. simplify and rewrite expressions. Identities. An equation is an identity if the left side is equal to the right side for all values of the variable...
Harappan Civilization ( also known as Indus Civilization) 2300-1750 BCE (or 2600-1900 BCE) Chapter 3, pp. 63-64 Harappa Name derived from one of its major city; Mohenjo Daro "city of the dead,"was another large city. The size of the area...
Honours in Psychology(info for the 2019 cohort) Presented by. ... Unlike anything you have done before - a large and sustained research project. Appreciate the importance of the research process in psychology, an evidence-based discipline.
Homophones Ashley stroked the hare's ears. hair Their books are on the desk. there, they're Do you know him? no In the first sentence, hare is an animal, but hair sounds just the same. Homophones What are some other homophone...
e: A CFC of a SA resident based in low tax jurisdiction owns undersea cables. It has full FBE, properly staffed. There are various commercial reasons why low tax jurisdiction was chosen for this purpose. MTN SA buys capacity from...
Arial MS Pゴシック Wingdings Calibri Arial Narrow Times New Roman Estat-Green 1_Estat-Green Microsoft Office Excel Worksheet House Price Developments in Europe Outline Background Legal Framework Macroeconomic surveillance (1) Macroeconomic surveillance (2) Macroeconomic surveillance (3) Imbalance indicators Scoreboard indicators Data ...
Frequency distributions and their graphs Frequency distribution tables give the number if instances of each value in a distribution. Frequency distribution graphs give a graphical depiction of the data in a frequency table.
Ready to download the document? Go ahead and hit continue!